Valuation: Spero Therapeutics, Inc.

Market Cap 72.96M 63.11M 58.93M 54.06M 102M 6.94B 103M 691M 271M 3.48B 274M 268M 11.51B P/E 2024
-0.81x
P/E 2025 15.5x
Enterprise Value 72.96M 63.11M 58.93M 54.06M 102M 6.94B 103M 691M 271M 3.48B 274M 268M 11.51B EV / Sales 2024
1,170,430x
EV / Sales 2025 -
Free-Float
77.49%
Yield 2024 *
-
Yield 2025 -
1 day-0.79%
1 week+7.69%
Current month+7.69%
1 month-41.94%
3 months-50.78%
6 months-47.93%
Current year-45.92%
1 week 1.12
Extreme 1.125
1.28
1 month 1.08
Extreme 1.08
2.34
Current year 1.08
Extreme 1.08
3.08
1 year 1.08
Extreme 1.08
3.08
3 years 0.51
Extreme 0.5052
3.22
5 years 0.51
Extreme 0.5052
19.87
10 years 0.51
Extreme 0.5052
23.64
Manager TitleAgeSince
Chief Executive Officer 47 10/01/2025
Chief Tech/Sci/R&D Officer 69 27/07/2026
Chief Operating Officer 58 01/02/2023
Director TitleAgeSince
Chairman 69 01/01/2014
Director/Board Member 62 01/09/2015
Chairman 56 10/01/2025
Date Insider Type Main position Quantity % Market Cap.
8/3/26 A Free

Chief Technology Officer

486,986 0.8411%
2/6/26 A Sell

Chief Executive Officer

87,917 0.1560%
2/6/26 A Sell

Chief Operating Officer

18,652 0.0331%
Change 5-day change 1-year change 3-year change Capi.($)
-0.79%+7.69%-42.47%-14.86% 72.96M
+8.49%+20.55%+70.77%+110.32% 68.12B
+1.25%+2.44%+34.27%+70.43% 55.18B
-1.09%+32.96%+19.67%+494.56% 28.63B
+10.83%+18.38%+56.20%+6.03% 23.99B
+2.72%+3.41%-16.11%-7.96% 23.53B
+6.50%+7.56%+44.65%-21.73% 18.45B
+6.20%+11.51%+33.87%+693.38% 16.44B
-3.88%+16.98%+199.30%+359.77% 15.83B
+3.58%+1.96%+43.35%+163.76% 13.4B
Average +3.38%+11.28%+44.35%+185.37% 26.36B
Weighted average by Cap. +4.36%+13.09%+50.66%+168.42%

Financials

2024 2025
Net sales 47.98M 41.5M 38.75M 35.55M 66.87M 4.57B 67.93M 455M 178M 2.29B 180M 176M 7.57B 66.8M 57.78M 53.96M 49.5M 93.11M 6.36B 94.58M 633M 248M 3.19B 251M 245M 10.53B
Net income -68.57M -59.31M -55.39M -50.81M -95.56M -6.53B -97.08M -650M -255M -3.27B -257M -252M -10.81B 8.57M 7.41M 6.92M 6.35M 11.95M 816M 12.14M 81.24M 31.89M 409M 32.19M 31.48M 1.35B
Net Debt - -
Logo Spero Therapeutics, Inc.
Spero Therapeutics, Inc. is a clinical-stage biopharmaceutical company. The Company is focused on identifying and developing novel treatments for rare diseases and diseases caused by multi-drug resistant (MDR) bacterial infections with unmet need. Its product candidate SPR720 is an investigational, chemically stable phosphate ester prodrug that is converted in vivo to SPR719 for the treatment of nontuberculous mycobacterial (NTM) pulmonary disease. Its clinical stage product candidate, tebipenem HBr is an investigational oral carbapenem antibiotic being developed for the treatment of complicated urinary tract infections (cUTIs) including acute pyelonephritis (AP) to help patients potentially reduce duration of in-patient therapy.
Employees
25
Date Price Change Volume
07/08/26 $1.260 -0.79% 459,025
06/08/26 $1.270 +0.79% 974,681
05/08/26 $1.260 +2.44% 574,907
04/08/26 $1.230 +6.96% 752,105
03/08/26 $1.150 -1.71% 1,373,121
Sell
Consensus
Buy
Mean consensus
HOLD
Number of Analysts
1
Last Close Price
1.260USD
Average target price
4.000USD
Spread / Average Target
+217.46%

Quarterly revenue - Rate of surprise

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