Valuation: Protagonist Therapeutics, Inc.

Market Cap 9.06B 7.94B 7.34B 6.75B 12.74B 874B 12.95B 87.79B 34.41B 428B 34.03B 33.29B 1,473B P/E 2026 *
35.7x
P/E 2027 * -123x
Enterprise Value 8.49B 7.44B 6.88B 6.32B 11.93B 819B 12.13B 82.23B 32.23B 400B 31.87B 31.18B 1,380B EV / Sales 2026 *
16.6x
EV / Sales 2027 * 52.2x
Free-Float
97.28%
Yield 2026 *
-
Yield 2027 * -
1 day-1.91%
1 week+6.51%
Current month+12.86%
1 month+20.27%
3 months+31.17%
6 months+65.84%
Current year+58.40%
1 week 126.97
Extreme 126.97
143.29
1 month 113.24
Extreme 113.24
143.29
Current year 77
Extreme 77
143.29
1 year 50.48
Extreme 50.485
143.29
3 years 13.72
Extreme 13.72
143.29
5 years 6.91
Extreme 6.91
143.29
10 years 4.47
Extreme 4.47
143.29
Manager TitleAgeSince
Chief Executive Officer 69 01/12/2008
Director of Finance/CFO 52 18/04/2022
Chief Tech/Sci/R&D Officer - 01/04/2026
Director TitleAgeSince
Director/Board Member 69 01/12/2008
Chairman 71 19/03/2014
Director/Board Member 69 01/07/2016
Date Insider Type Main position Quantity % Market Cap.
6/23/26 A Fiscal year

Director

27,000 0.0420%
6/10/26 A Fiscal year

Director

27,000 0.0420%
5/29/26 A Fiscal year

Director

27,000 0.0420%
Change 5-day change 1-year change 3-year change Capi.($)
-2.30%+6.51%+150.53%+595.20% 9.06B
-0.49%-4.01%+0.61%+2.28% 49.18B
-1.50%-0.13%+378.16%+584.97% 39.58B
-0.49%+2.77%+7.01%+61.95% 34.69B
-0.54%-0.97%+29.30%-9.20% 34.42B
-1.82%-1.48%+0.52%+32.02% 27.11B
-2.49%-4.12% - - 16.21B
-0.89%+0.74%+72.92%+116.33% 15.36B
+1.17%+2.30%+15.46%+18.26% 14.05B
-2.15%+0.28%+19.29%-32.68% 13.02B
Average -0.94%+0.57%+74.87%+152.13% 25.27B
Weighted average by Cap. -0.79%-0.11%+81.25%+139.45%

Financials

2026 *2027 *
Net sales 512M 448M 415M 381M 719M 49.34B 731M 4.96B 1.94B 24.14B 1.92B 1.88B 83.17B 163M 143M 132M 121M 229M 15.69B 232M 1.58B 618M 7.68B 611M 598M 26.45B
Net income 249M 218M 201M 185M 349M 23.97B 355M 2.41B 944M 11.73B 933M 913M 40.41B -82.92M -72.68M -67.18M -61.79M -117M -8B -118M -803M -315M -3.91B -311M -305M -13.48B
Net Debt -574M -503M -465M -428M -807M -55.34B -820M -5.56B -2.18B -27.08B -2.16B -2.11B -93.3B -565M -495M -458M -421M -794M -54.46B -807M -5.47B -2.14B -26.65B -2.12B -2.07B -91.8B
Logo Protagonist Therapeutics, Inc.
Protagonist Therapeutics, Inc. is a biopharmaceutical company with a technology platform that enables de novo discovery of peptide therapeutics. The Company's programs fall into three therapeutic areas: inflammation and immunology (I&I), hematology, and metabolic diseases. Its clinical and pre-clinical programs address biologically and commercially validated targets, including IL-17 oral peptide antagonist PN-881, obesity triple agonist peptide PN-477, obesity dual agonist peptide PN-458, oral small molecule hepcidin functional mimetic PN-8047, and IL-4 and amylin programs. The ICOTYDE (icotrokinra) is used for the treatment of moderate-to-severe plaque psoriasis in adults and pediatric patients 12 years of age or older who weigh at least 40 kg and are candidates for systemic therapy or phototherapy. Rusfertide is an investigational injectable mimetic of the natural hormone hepcidin in development for the treatment of the rare blood disorder polycythemia vera (PV).
Employees
131
Date Price Change Volume
20/07/26 $138.11 -1.99% 279,235
17/07/26 $140.91 +6.73% 519,116
16/07/26 $132.02 -2.54% 602,064
15/07/26 $135.46 +3.19% 836,109
14/07/26 $131.27 +1.06% 564,974
Trader
Investor
Global
Quality
ESG MSCI
BB
Sell
Consensus
Buy
Mean consensus
BUY
Number of Analysts
13
Last Close Price
140.91USD
Average target price
125.15USD
Spread / Average Target
-11.18%

Quarterly revenue - Rate of surprise

  1. Stock Market
  2. Stocks
  3. PTGX Stock