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Valuation: Septerna, Inc.

Market Cap 1.61B 1.41B 1.3B 1.22B 2.28B 152B 2.3B 15.42B 5.99B 74.95B 6.06B 5.93B 260B P/E 2026 *
-20.8x
P/E 2027 * -15x
Enterprise Value 1.26B 1.1B 1.02B 956M 1.79B 119B 1.8B 12.09B 4.69B 58.74B 4.75B 4.65B 204B EV / Sales 2026 *
16.4x
EV / Sales 2027 * 16.8x
Free-Float
97.17%
Yield 2026 *
-
Yield 2027 * -
1 day-1.35%
1 week+3.75%
Current month+16.90%
1 month+34.24%
3 months+46.43%
6 months+28.20%
Current year+26.63%
1 week 33.85
Extreme 33.85
37.32
1 month 25.79
Extreme 25.79
37.32
Current year 22.78
Extreme 22.78
37.32
1 year 9.96
Extreme 9.96
37.32
3 years 4.17
Extreme 4.17
37.32
5 years 4.17
Extreme 4.17
37.32
10 years 4.17
Extreme 4.17
37.32
Manager TitleAgeSince
Chief Executive Officer 60 01/11/2021
Director of Finance/CFO 55 06/01/2025
President 58 01/08/2025
Director TitleAgeSince
Director/Board Member 60 01/11/2021
Chairman 50 01/11/2021
Director/Board Member 41 01/11/2021
Date Insider Type Main position Quantity % Market Cap.
06-12Fiscal year

Head of Human Resources

18,750 0.0416%
06-01Fiscal year

Head of Human Resources

17,805 0.0395%
05-26Fiscal year

Head of Human Resources

35,394 0.0788%
Change 5-day change 1-year change 3-year change Capi.($)
-1.30%+3.75%+236.56% - 1.61B
-0.34%-0.08%-12.15%-10.46% 43.44B
+2.30%+8.09%+303.96%+528.12% 33.54B
-1.45%-8.01%+7.72%-22.51% 28.48B
+2.43%+3.26%+6.32%+40.29% 29.2B
-0.57%+3.77%+12.66%+20.42% 25.34B
+0.13%+7.58% - - 14.36B
+0.46%-3.31%+51.76%+103.90% 13.05B
+0.54%-2.27%+3.93%+4.80% 12.67B
+0.02%+0.80%+101.05%+81.18% 12.28B
Average +0.22%+2.47%+79.09%+93.22% 21.4B
Weighted average by Cap. +0.43%+0.92%+63.82%+104.67%

Financials

2026 *2027 *
Net sales 76.94M 67.04M 61.8M 58.13M 109M 7.25B 110M 735M 286M 3.57B 289M 283M 12.39B 65.86M 57.39M 52.9M 49.76M 93.09M 6.21B 93.74M 629M 244M 3.06B 247M 242M 10.6B
Net income -76.38M -66.55M -61.35M -57.71M -108M -7.2B -109M -730M -283M -3.55B -287M -281M -12.3B -121M -105M -97.24M -91.47M -171M -11.41B -172M -1.16B -449M -5.62B -454M -445M -19.49B
Net Debt -349M -304M -280M -264M -493M -32.88B -497M -3.33B -1.29B -16.2B -1.31B -1.28B -56.17B -508M -443M -408M -384M -719M -47.92B -724M -4.86B -1.89B -23.62B -1.91B -1.87B -81.85B
Logo Septerna, Inc.
Septerna, Inc. is a clinical-stage biotechnology company. The Company is developing G protein-coupled receptor (GPCR) oral small-molecule drug discovery powered by its proprietary Native Complex Platform. Its pipeline of product candidates is focused on treating patients in three therapeutic areas: endocrinology, immunology and inflammation, and metabolic diseases. Its industrial-scale Native Complex Platform is designed to target certain GPCRs for the first time, uncover novel binding pockets for validated receptors, and pursue a wide spectrum of pharmacologies, including agonists, antagonists, and allosteric modulators, to achieve desired therapeutic effects. It is advancing a deep portfolio of oral small molecule GPCR-targeted programs with novel mechanistic approaches to treat diseases across multiple therapeutic areas for patients with unmet needs. It is focused on therapeutic areas, such as neurology, women’s health, cardiovascular, and respiratory disease.
Employees
130
Date Price Change Volume
18/06/26 35.24 $ -1.56% 144,525
17/06/26 35.80 $ +1.79% 325,299
16/06/26 35.17 $ -2.39% 284,028
15/06/26 36.03 $ +0.22% 287,821
12/06/26 35.95 $ +5.64% 475,864
Trader
Investor
-
Global
-
Quality
-
ESG MSCI
BB
Sell
Consensus
Buy
Mean consensus
BUY
Number of Analysts
10
Last Close Price
35.80USD
Average target price
45.78USD
Spread / Average Target
+27.87%

Quarterly revenue - Rate of surprise

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