Valuation: Prothena Corporation plc

Market Cap 455M 400M 372M 342M 642M 43.51B 653M 4.42B 1.73B 21.58B 1.71B 1.67B 74.56B P/E 2026 *
-121x
P/E 2027 * -8.84x
Enterprise Value 455M 400M 372M 342M 642M 43.51B 653M 4.42B 1.73B 21.58B 1.71B 1.67B 74.56B EV / Sales 2026 *
5.47x
EV / Sales 2027 * 20.7x
Free-Float
79.82%
Yield 2026 *
-
Yield 2027 * -
1 day-1.61%
1 week-2.17%
Current month-12.56%
1 month-14.14%
3 months-25.63%
6 months-6.35%
Current year-10.37%
1 week 8.23
Extreme 8.23
9.13
1 month 8.08
Extreme 8.075
10.15
Current year 7.73
Extreme 7.73
11.8
1 year 6.61
Extreme 6.61
11.8
3 years 4.32
Extreme 4.32
70.09
5 years 4.32
Extreme 4.32
79.75
10 years 4.32
Extreme 4.32
79.75
Manager TitleAgeSince
Chief Executive Officer 57 30/09/2016
Director of Finance/CFO 52 01/04/2013
Chief Operating Officer 52 29/09/2021
Director TitleAgeSince
Chairman 76 20/12/2012
Director/Board Member 72 20/12/2012
Director/Board Member 63 20/12/2012
Date Insider Type Main position Quantity % Market Cap.
6/16/26 A Buy 20,000 0.0382%
6/15/26 A Don -325,000 0.6208%
6/11/26 A Buy 125,000 0.2388%
Change 5-day change 1-year change 3-year change Capi.($)
-1.61%-2.17%+24.60%-87.17% 455M
-2.25%+2.44%+53.17%+64.57% 56.19B
-1.32%-0.97%+38.41%+77.52% 54.83B
+1.49%+0.13%-18.03%-13.94% 23.04B
-0.57%-4.13%+2.34%+387.73% 22.7B
-0.21%+0.84%+22.48%-7.92% 20.23B
0.00%+3.30%+28.01%-29.07% 17.83B
-0.97%+0.89%+37.28%+539.62% 15.65B
-6.69%-5.11%+166.00%+304.89% 15.24B
+1.25%+0.69%+27.30%+184.69% 14.03B
Average -1.09%+0.01%+38.16%+142.09% 24.02B
Weighted average by Cap. -1.17%+0.42%+38.27%+130.41%

Financials

2026 *2027 *
Net sales 83.32M 73.12M 68.09M 62.63M 117M 7.96B 119M 808M 316M 3.95B 313M 306M 13.64B 22M 19.31M 17.98M 16.54M 31M 2.1B 31.53M 213M 83.49M 1.04B 82.59M 80.81M 3.6B
Net income 2.42M 2.13M 1.98M 1.82M 3.41M 232M 3.47M 23.49M 9.2M 115M 9.1M 8.9M 397M -55.93M -49.08M -45.71M -42.04M -78.8M -5.34B -80.15M -542M -212M -2.65B -210M -205M -9.16B
Net Debt - -
Logo Prothena Corporation plc
Prothena Corporation plc is an Ireland-based late-stage clinical biotechnology company. The Company is engaged in protein dysregulation and a pipeline of investigational therapeutics for rare peripheral amyloid diseases. The Company is advancing a pipeline of therapeutic candidates for a range of indications and targets to integrate scientific insights around neurological dysfunction and the biology of misfolded proteins. The Company’s pipeline includes both wholly owned and partnered programs being developed for the potential treatment of diseases, including AL amyloidosis, ATTR amyloidosis, Alzheimer’s disease, Parkinson’s disease and a range of other neurodegenerative diseases. Its clinical programs include birtamimab for the potential treatment of AL amyloidosis, prasinezumab for the potential treatment of Parkinson’s disease, NNC6019/PRX004 for the potential treatment of ATTR amyloidosis, and PRX005 and PRX012 for the potential treatment of Alzheimer’s disease.
Employees
67
Date Price Change Volume
28/07/26 $8.560 -1.61% 802,244
27/07/26 $8.700 -0.57% 704,707
24/07/26 $8.750 +2.58% 576,837
23/07/26 $8.530 +1.07% 532,213
22/07/26 $8.440 -3.54% 542,549
Trader
Investor
-
Global
-
Quality
-
ESG MSCI
BBB
Sell
Consensus
Buy
Mean consensus
OUTPERFORM
Number of Analysts
6
Last Close Price
8.700USD
Average target price
21.40USD
Spread / Average Target
+145.98%

Quarterly revenue - Rate of surprise

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