Valuation: Karyopharm Therapeutics Inc.

Market Cap 169M 148M 137M 126M 238M 16.33B 242M 1.64B 643M 7.99B 636M 622M 27.52B P/E 2026 *
-1.79x
P/E 2027 * -2.41x
Enterprise Value 422M 370M 342M 315M 594M 40.72B 603M 4.09B 1.6B 19.92B 1.59B 1.55B 68.65B EV / Sales 2026 *
3.08x
EV / Sales 2027 * 1.09x
Free-Float
95.32%
Yield 2026 *
-
Yield 2027 * -

Last Transcript: Karyopharm Therapeutics Inc.

1 day-21.45%
1 week-25.67%
Current month-23.54%
1 month-17.18%
3 months-16.44%
6 months+25.55%
Current year+1.49%
1 week 6.48
Extreme 6.485
9.86
1 month 6.48
Extreme 6.485
10.86
Current year 5
Extreme 5
10.99
1 year 3.65
Extreme 3.6503
10.99
3 years 3.51
Extreme 3.51
29.25
5 years 3.51
Extreme 3.51
220.95
10 years 3.51
Extreme 3.51
444.15
Manager TitleAgeSince
Chief Executive Officer 58 03/05/2021
Director of Finance/CFO 55 03/01/2025
Chief Tech/Sci/R&D Officer - 01/04/2023
Director TitleAgeSince
Director/Board Member 62 01/01/2013
Director/Board Member 61 01/04/2013
Director/Board Member 78 03/10/2013
Date Insider Type Main position Quantity % Market Cap.
5/21/26 A Free

Director

15,508 0.0688%
5/21/26 A Free

Director

15,508 0.0688%
5/21/26 A Free

Director

15,508 0.0688%
Change 5-day change 1-year change 3-year change Capi.($)
-21.45%-25.67%+94.03%-69.07% 169M
-0.67%+1.37%+23.89%-7.04% 68.38B
+0.13%+2.49%+37.51%+190.54% 51.69B
-3.65%+34.50%+34.50%+34.50% 42.1B
-1.00%-1.28%-52.46%-54.56% 41.11B
-2.93%-4.34%+59.97%-27.21% 29.52B
-3.77%-11.22%+90.31%-52.32% 23.6B
-1.36%+1.24%+70.42%+80.67% 23.1B
+0.11%+2.67%+4.29%+181.86% 20.54B
-0.04%+1.85%+71.90%+121.88% 16.53B
Average -3.48%-3.70%+43.44%+39.93% 31.67B
Weighted average by Cap. -1.41%-0.88%+30.59%+44.65%

Financials

2026 *2027 *
Net sales 137M 120M 111M 102M 193M 13.23B 196M 1.33B 521M 6.47B 515M 504M 22.3B 155M 136M 126M 116M 218M 14.98B 222M 1.5B 590M 7.33B 583M 570M 25.24B
Net income -121M -106M -98.05M -90.18M -170M -11.67B -173M -1.17B -460M -5.71B -454M -445M -19.67B -135M -118M -109M -100M -189M -12.97B -192M -1.3B -511M -6.35B -505M -494M -21.87B
Net Debt 253M 222M 205M 189M 356M 24.4B 361M 2.45B 961M 11.94B 950M 929M 41.13B -
Logo Karyopharm Therapeutics Inc.
Karyopharm Therapeutics Inc. is a commercial-stage pharmaceutical company. The Company is engaged in the discovery, development and commercialization of drugs directed against nuclear export for the treatment of cancer. It is developing and commercializing novel, small molecule XPO1 inhibitor compounds that inhibit the nuclear export protein exportin 1 (XPO1). Its lead asset, XPOVIO (selinexor), is marketed in combination with bortezomib and dexamethasone for the treatment of adult patients with multiple myeloma who have received at least one prior therapy. XPOVIO is also marketed for treatment of adult patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL). The Company is engaged in evaluating selinexor in certain hematological and solid tumor malignancies, including myelofibrosis, endometrial cancer and multiple myeloma. The Company’s product candidate, eltanexor, is an oral SINE compound like selinexor, that selectively blocks the nuclear export protein XPO1.
Employees
228
Date Price Change Volume
20/07/26 $7.470 -21.45% 2,330,172
17/07/26 $9.510 +1.39% 205,243
16/07/26 $9.380 -1.57% 236,381
15/07/26 $9.530 -4.80% 316,488
14/07/26 $10.01 -0.40% 481,544
Trader
Investor
-
Global
-
Quality
-
ESG MSCI
-
Sell
Consensus
Buy
Mean consensus
BUY
Number of Analysts
7
Last Close Price
7.470USD
Average target price
13.50USD
Spread / Average Target
+80.72%

Quarterly revenue - Rate of surprise

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